A third kidney transplant: cost-effective treatment for end-stage renal disease?
نویسندگان
چکیده
Given the organ donor shortage, some question whether a third kidney transplant can be justified. We studied the outcome of 51 third transplants (mean age 28 +/- 2 yr) done between 1 January 1985 and 31 December 1994. We compared hospital stay (mean +/- S.E.), cost, readmissions, readmission days, and outcome of third (vs. first and second) transplants. We found that patient survival for third transplants was equivalent to first and second transplants; graft survival was not as good. However, when third transplant recipients with recurrent disease (specifically, hemolytic uremic syndrome and focal sclerosis) were excluded from our analysis, we found no difference in 5-yr graft survival (vs. first or second transplant recipients). Of the 51 third transplant recipients, 41 had a cadaver donor transplant. Third cadaver transplant recipients tended to have a longer hospital stay (p = NS) than first cadaver transplant recipients but had no more readmissions or readmission days than first and second cadaver transplant recipients. Employment data are available for 28 third transplant recipients; 16 (57%) are currently working or going to school. Of the 21 recipients who responded to quality of life questionnaires, 17 (81%) reported being healthy and all 21 (100%) said transplantation was not a drawback to their health. We conclude that third transplants should be considered for selected patients with renal failure whose first and second transplants have failed. Such patients can often be successfully transplanted.
منابع مشابه
Evaluation the Cause of End-Stage Renal Disease (ESRD) in Kidney Transplant Patients-A Single Center Study
متن کامل
BK Viremia among Iranian Renal Transplant Candidates
Background: Primary infection with BK virus (BKV) is occurred during childhood and usually asymptomatic, but after initial infection, BKV may persist lifelong in the kidney and genitourinary tract. Reactivation may occur in individuals with compromised immunity such as renal transplant recipients. Due to the role of BKV in BK virus-associated nephropathy (BKVAN) and po...
متن کاملEtiology and Outcome of Chronic Kidney Disease in Iranian Children
Background Considering the significant geographical and ethnical differences in pattern of incidence, etiology and outcome of chronic kidney disease (CKD), the present study aimed to assess the etiology and outcome of CKD in Iranian children. Materials and Methods In a cross-sectional study etiology and outcome of 372 children aged 3 months to 18 years with CKD was studied during the period 199...
متن کاملEarly dysfunction of transplanted kidney revealed the cause of recurrent nephrolithiasis: a case report of primary hyperoxaluria
Primary hyperoxaluria (PH) disorder causes end-stage renal disease (ESRD). Missed diagnosis or relapse in transplanted kidney is common. We present a 36-year-old patient with a history of recurrent renal calculus which progressed to end-stage renal disease. He underwent kidney-transplant surgery. Renal function tests had worsening progressively at first-week post-transplant. Transplanted kidney...
متن کاملگزارش یک مورد آنژیوپلاستی و Stent گذاری موفق در درمان تنگی
Introduction: Renal transplantation has established itself as the treatment of choice for the majority of patients with End stage renal failure(ESRF). Arterial stenosis is the most common vascular complication after kidney transplantation, occurring in approximately 4%-25% of transplant recipients. Case Report: The patient is a 68 year old man with ESRF due to Poly cystic kidney disease(PCK...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Clinical transplantation
دوره 10 6 Pt 1 شماره
صفحات -
تاریخ انتشار 1996